Apigenin

What is Apigenin?

Apigenin is a natural flavonoid found in several plants, including chamomile, parsley, celery, and citrus fruits. It belongs to a larger family of polyphenols and is known for its many health benefits. Apigenin stands out for its calming and anti-inflammatory properties, which have made it an interesting subject for researchers and health enthusiasts. Many people use apigenin to promote relaxation and support the immune system.

How does it work in the body?

Apigenin works by interacting with various biological processes in the body. It is known to have a modulatory effect on neurotransmitters, which can contribute to a sense of calm and relaxation. Additionally, apigenin has been shown to inhibit the enzyme CD38, which may help preserve levels of NAD+ (nicotinamide adenine dinucleotide), an important molecule for energy metabolism and cellular repair. By preserving NAD+, apigenin can support cellular health and counteract ageing.

Scientific benefits

Several studies have investigated the potential health benefits of apigenin. Here are some of the most prominent:

• Anti-inflammatory properties: According to research published in the Journal of Nutritional Biochemistry, apigenin may help reduce inflammation in the body by inhibiting pro-inflammatory cytokines.
• Calming effect: A study published in Phytotherapy Research showed that apigenin may have an anxiolytic effect, making it useful for those suffering from stress and anxiety.
• Antioxidant activity: Apigenin has demonstrated strong antioxidant properties, which may help protect cells from oxidative stress, according to research published in Food and Chemical Toxicology.
• Potential for cancer prevention: Several in vitro studies have suggested that apigenin may have antitumour properties by inhibiting cancer cell growth and inducing apoptosis (programmed cell death).

Dosage and recommendations

There is no official recommended dosage for apigenin, but many supplements containing apigenin range between 50 mg and 500 mg per day. It is important to consult a doctor or dietitian before starting to take apigenin as a supplement, especially if you are pregnant, breastfeeding, or have an underlying health condition.

Best sources and forms

Apigenin can be consumed through various foods and supplements. Here are some of the best sources:

• Chamomile: Chamomile tea is an excellent source of apigenin and is often used for its calming properties.
• Parsley: Parsley is another plant containing high levels of apigenin and can easily be added to various dishes.
• Celery: Celery is not only healthy but also rich in apigenin.
• Supplements: Apigenin is also available as a supplement in capsule or tablet form, which can be a convenient option for those wishing to increase their intake.

Side effects and warnings

Although apigenin is considered safe for most when consumed in normal amounts, some individuals may experience side effects. Common side effects may include:

• Nausea
• Headache
• Allergic reactions (especially in people allergic to plants in the Asteraceae family)

It is important to speak with a healthcare professional before starting apigenin, especially if you are taking other medications or have health issues.

Frequently asked questions

What is apigenin good for?

Apigenin is known for its calming, anti-inflammatory, and antioxidant properties, and it may potentially help manage anxiety and inflammation.

Can I get apigenin from my diet?

Yes, apigenin naturally occurs in foods such as chamomile, parsley, and celery, making it possible to obtain through a balanced diet.

Is apigenin safe to take as a supplement?

Generally, apigenin is considered safe, but it is important to consult a doctor before use, especially for pregnant or breastfeeding women.

Are there any interactions with medications?

Apigenin may interact with certain medications, especially those affecting blood coagulation. It is important to discuss any potential interactions with a doctor.

How long does it take before I feel the effects of apigenin?

The time to feel effects may vary depending on the individual and dosage, but many report feeling a calming effect within a few hours after intake.